Structural Modification of Proteins and Peptides
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- 1Department of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, Pushp Vihar, Sector-3, M. B. Road, New Delhi, India – 110017.
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Anubha Mahajan
Department of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, Pushp Vihar, Sector-3, M. B. Road, New Delhi, India – 110017.
Volume 48, Issue 3 · pp. 34-47 · 2014 · DOI: 10.5530/ijper.48.3.6
ABSTRACT
Proteins and peptides are ubiquitous in every cell and thus are vital for various biological functions. In recent years, there is an extensive growth in the development of various biologicals and large molecules like proteins and peptides. Now, they are replacing the market of existing organic based pharmaceuticals. This review article intends to summarize various structural modifications that are carried out in order to alter basic properties of peptides and proteins so that their solubility, absorption, permeability and various other problems associated with their delivery can be resolved. Thus they can offer significant therapeutic potential.
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Mahajan, A., Rawat, A. S., Bhatt, N., & Chauhan, M. K. (2014). Structural Modification of Proteins and Peptides. Indian Journal of Pharmaceutical Education and Research, 48(3), 34-47. https://doi.org/10.5530/ijper.48.3.6
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© 2014 Author(s)
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. CC BY 4.0