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Recent articles
15 articles · what your feed deliversReview Article
Stress-Induced Gastritis: A Comprehensive Literature Review on Etiology and Treatment
Shravya Lakshmi Somashekar, Kiran Kumar Gubbi Basavaraju, Devegowda Vishakante Gowda
Volume 61, Issue 1 · pp. 1-14 · 2026
Gastritis is a common gastrointestinal disorder with multiple etiologies, including infections, medication use, autoimmune conditions, and psychosocial stress. Among these, stress-induced gastritis remains unrecognized despite its increasing incidence in high-stress…
Review Article
Microneedles as Novel Drug Delivery Platforms: Fabrication Techniques, Evaluation Methods, and Clinical Potential
Yogesh Ashok Sonar, Hitendra Shaligram Mahajan
Volume 61, Issue 1 · pp. 15-23 · 2026
Microneedle-based drug delivery has received considerable attention and is rapidly approaching commercialisation owing to the availability of different scalable techniques to yield various microneedles. Numerous materials such as metals, silicones, polymers, and carbohydrates…
Review Article
Natural Compounds in Cancer Chemoprevention: Mechanisms, Challenges, and Future Prospects
Sangeetha Saravanan, Anandharaj Govindaraj, Rajinikanth Baskaran, Gomathy Subramanian
Volume 61, Issue 1 · pp. 24-32 · 2026
Cancer remains a significant global health challenge, with increasing incidence rates despite advancements in treatment modalities. Chemoprevention, utilising natural or synthetic agents to hinder, delay, or reverse carcinogenesis, has emerged as a promising approach to reduce…
Review Article
Migraine Disorders: Pathophysiology and Emerging Liposomal Drug Delivery Approaches
Sanjana Katlaria, Yogita Tyagi
Volume 61, Issue 1 · pp. 33-42 · 2026
Migraine is a complicated neurovascular condition that significantly impairs quality of life and productivity, affecting over one billion individuals worldwide. While conventional therapies such as NSAIDs, triptans, and ergot derivatives provide temporary relief, their…
Review Article
Vitamin D in NAFLD, Diabetes, and Depression: A Mechanistic Link
Kirti Barkale, Gauri Khaladkar, Gayatri Kotwal, Umesh Laddha, Gangadhar Magar
Volume 61, Issue 1 · pp. 43-53 · 2026
Background: Non-Alcoholic Fatty Liver Disease (NAFLD), Type 2 Diabetes Mellitus (T2DM), and depression are interlinked chronic conditions that share common pathophysiological mechanisms such as insulin resistance, chronic inflammation, and oxidative stress. Emerging evidence…
Review Article
Unlocking Cardiovascular Health: The Synergy of Genetics, Pharmacotherapy, Comorbidities, and Herbal Medicine
Pallavi Bolade Manjunatha, Gunavathi Honnashettihalli Dharmaraj, Prasad Bettadasathenhalli Verabhadrappa, Hemanth Prasad Konasuru Puttaraju, Sirivennala Murali Mohan, Abhishek Pete Nagaraj
Volume 61, Issue 1 · pp. 54-65 · 2026
Cardiovascular Diseases (CVDs) are still a leading cause of morbidity and mortality worldwide, which has led to increased research in personalized approaches to therapy, new drug targets, and more understanding of comorbidities. The importance of the CYP2C19 polymorphisms and…
Review Article
Review on Exploring the Role of Short-Chain Fatty Acids in Neuroinflammation: Mechanisms and Therapeutic Perspectives
Patnam Nageswari, Karri Swathi Priya, Ketha Srilekhya, Yaso Deepika, Surya Neeraja Nagalla, Shashikala Metri, Mattakoyya Jhansi Rani, Bandaru Nagaraju, Jamal Bati Kuresa
Volume 61, Issue 1 · pp. 66-76 · 2026
Alzheimer's disease, Parkinson's disease, multiple sclerosis, and autism spectrum disorders are only a few of the neurodegenerative and neuropsychiatric conditions that are significantly influenced by neuroinflammation. The gut microbiota produces Short-Chain Fatty Acids…
Original Article
The Application of a Team-Based Learning Approach Enhances Students' Academic Performance
Mohamed M A E L Salem, Mohammed A M Salih, Hanin M M Salem, Muhammad Shahid, Amjad Shahzad
Volume 61, Issue 1 · pp. 77-83 · 2026
Objectives: This study evaluated the implementation of a Team-Based Learning modified TBL approach in Biotechnology and Chemistry modules at the University of Azad Jammu and Kashmir and explored its impact on students' academic performance and perceptions. Background:…
Original Article
Formulation, Optimization, and in vivo Evaluation of Repaglinide-Loaded Solid Lipid Nanoparticles with Enhanced Bioavailability and Sustained Hypoglycemic Effect
Vedanshu Malviya, Shrikant Pande
Volume 61, Issue 1 · pp. 84-99 · 2026
Background: Repaglinide is an oral antidiabetic agent which has inadequate water solubility and is highly first-pass metabolized (poor bioavailability 50-60%), thus necessitating frequent administration. Solid Lipid Nanoparticles (SLNs) present a promising approach to improve…
Original Article
Design, Optimization, and Characterization of Atorvastatin-Loaded Lipid-based Carriers for Enhanced Oral Bioavailability
Mohini Mondal, Biplab Debnath, Swarupananda Mukherjee, Tapan Kumar Shaw
Volume 61, Issue 1 · pp. 100-109 · 2026
Aim: This study presents a dose reduction with sustained action and increased bioavailability. Atorvastatin (ATV) is the drug of choice for the management of hyperlipidemia, and the commonly available marketed product of ATV is tablets. ATV is a poorly water-soluble drug showing…
Original Article
PLGA Nanoparticle-Embedded Oral Films for Sustained Eletriptan Delivery
Anju Bala, Inderjeet Verma, Chander Parkash Dora, Km Saiphali, Kapil Kumar, Tarun Kapoor
Volume 61, Issue 1 · pp. 110-126 · 2026
Objectives: The study aimed to fabricate and characterize Oral Dispersible Film (ODF) containing PLGA polymeric nanoparticles of Eletriptan Hydrobromide (EH). The ODF system is designed to circumvent pre-systemic metabolism of drug and thereby augment the issue of low oral…
Original Article
Anticancer Potential of Ligustilide Derived from Extract of Angelica sinensis against Colon Cancer: In vitro and Computer Molecular Docking Studies
Heng Li
Volume 61, Issue 1 · pp. 127-136 · 2026
Background: Colorectal cancer is a substantial global health issue, requiring the advancement of innovative therapeutic strategies beyond traditional methods. Despite progress in treatment options, colorectal cancer continues to be the second most fatal cancer worldwide, with…
Original Article
Thymoquinone Ameliorates Oxidative Stress and Inflammatory Responses and Protects against Monosodium Iodoacetate-Induced Osteoarthritis in Rats
Wenfeng Shi, Yugang Li, Zhu Shi
Volume 61, Issue 1 · pp. 137-146 · 2026
Background: Osteoarthritis is a degenerative joint condition defined by the destruction of cartilage, resulting in pain, stiffness, and impaired joint function. There is a growing need for safe and effective therapies that can address the underlying causes of osteoarthritis and…
Original Article
Nephroprotective Effects of Sarsasapogenin in Adenine-Induced Chronic Kidney Failure in Experimental Rats
Zhenzhen Hao, Minhua Xiao, Yan Gao, Qian Wang, Jing Li, Li Guo
Volume 61, Issue 1 · pp. 147-155 · 2026
Background: Chronic Kidney Disease (CKD), characterized by a progressive decrease in kidney function, has become a prominent health issue worldwide. The limitations of existing therapeutics for CKD underscore the pressing need for safe and effective alternative therapies that…
Original Article
Investigating the Multimodal Mechanism of a Polyherbal Anti-Diabetic Preparation Using 3T3-L1 adipocytes, C2C12 myotubes, and βTC-6 β-Cell Line Models
Venkatesh Uppara, Bachu Venkata Ramana
Volume 61, Issue 1 · pp. 156-168 · 2026
Introduction: Hyperglycaemia is a complicated condition that includes reduced production of insulin, resistance towards insulin, and oxidative imbalance. Current therapies often have limited efficacy and adverse effects, prompting interest in safer, multitarget alternatives.…