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Antiobesity Potential of Fresh Cow Urine and its Distillate - A Biomedicine for Tomorrow

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  1. 1NMIMS, School of Pharmacy and Technology Management, Shirpur, Maharashtra, INDIA.

CORRESPONDENCE

Sanjay Sharma

NMIMS School of Pharmacy and Technology Management, Shirpur, Maharashtra, INDIA.

sanjay.sharma@nmims.edu

Received: 17-08-2017; Accepted: 28-10-2017.

Volume 51, Issue 4s (Supplement) · pp. s712-s721 · 2017 · DOI: 10.5530/ijper.51.4s.103

ABSTRACT

Background: The cow urine has been used traditionally for the management of many diseases and also used as bio-enhancer to improve their therapeutic effect.Objective: To prepare and evaluate the anti-obesity potential of distillate cow urine and compare with fresh cow urine against high fat diet induced obesity in Wistar rats.Materials and Methods: Qualitative analysis of fresh cow urine and its distillate was done and used for the evaluation of assessment of anti-obesity parameters like BMI, abdominal circumference, obesity index, atherogenic index, lipid profile analysis and histopathological evaluation after two months daily oral treatment against high fat diet induced Obesity.Results: The treated groups with fresh cow urine and its distillate has reduced BMI, abdominal circumference, obesity index, atherogenic index, total cholesterol, triglycerides, LDL-C and VLDL-C Significantly while increased the levels of HDL-C as compared with control group (P<0.05). The Histopathological evaluation revealed the size of visceral white adipose tissue in treated groups was reduced as compared with control Group.Conclusion: In the present research conclude that fresh cow urine and its distillate both are having significant anti-obesity activity against high fat diet induced obesity in Wistar rats.

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    Sharma, S., Hatware, K., Deshpande, A., Dande, P., & Karri, S. (2017). Antiobesity Potential of Fresh Cow Urine and its Distillate - A Biomedicine for Tomorrow. Indian Journal of Pharmaceutical Education and Research, 51(4s), s712-s721. https://doi.org/10.5530/ijper.51.4s.103

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    © 2017 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. CC BY 4.0