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Biologically Active Metal Complexes Containing Thiazole core: Synthesis and Spectral Characterization

1,2, 1

  1. 1Department of Studies and Research in Chemistry, Gulbarga University, Kalburagi, Karnataka, INDIA.
  2. 2Department of Chemistry, Aditya Women’s Science and Commerce Degree College, Bhalki, Karnataka, INDIA.

CORRESPONDENCE

Bennikallu Hire Mathada Mruthyunjayaswamy

Department of Studies and Research in Chemistry, Gulbarga University, Kalburagi, Karnataka, INDIA.

bhmmswamy53@ rediffmail.com

Received: 18-04-2017; Accepted: 31-12-2017.

Volume 52, Issue 2 · pp. 255-261 · 2018 · DOI: 10.5530/ijper.52.2.29

ABSTRACT

The present study deals with the synthesis of new ligand N-(4-phenylthiazol-2-yl)-2 (pyridin-2-yl-methylene) hydrazinecarboxamide and it’s Cu (II), Co (II), Ni (II) and Zn (II) complexes and study their antimicrobial activity. The newly prepared compounds are characterized by elemental analysis, FT-IR, 1H NMR, mass, UV-visible and ESR spectral techniques. The elemental analysis data and spectral study indicates octahedral geometry for Cu (II), Co (II) and Ni (II) complexes and tetrahedral geometry for Zn (II) complex. All the compounds were tested for antimicrobial activity, the Cu (II) and Co (II) complexes showed good antimicrobial activity.

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    Yernale, N. G., & Mruthyunjayaswamy, B. H. M. (2018). Biologically Active Metal Complexes Containing Thiazole core: Synthesis and Spectral Characterization. Indian Journal of Pharmaceutical Education and Research, 52(2), 255-261. https://doi.org/10.5530/ijper.52.2.29

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    © 2018 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. CC BY 4.0