Indian Journal of Pharmaceutical Education and Research logo
Submit
Indian Journal of Pharmaceutical Education and ResearchAn Official Publication of Association of Pharmaceutical Teachers of India (APTI)
Review

Chemistry and Pharmacology of Flavonoids- A Review

1, 1

  1. 1Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra, Haryana- 136119, INDIA.

CORRESPONDENCE

Avtar Chand Rana

Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra, Haryana- 136119, INDIA.

acrana4@yahoo.com

Received: 24-08-2018; Accepted: 10-11-2018.

Volume 53, Issue 1 · pp. 8-20 · 2019 · DOI: 10.5530/ijper.53.1.3

ABSTRACT

Several modern and most of the traditional drugs have been developed from natural sources. Flavonoids or bioflavonoids, most ubiquitous polyphenolic compounds, are secondary metabolites of plants and fungal origin. Apart from their biological functions in plants (protection against herbivores, ultraviolet radiation and pathogens), they perform myriads of pharmacological activities in humans as well. Though flavonoids are not acknowledged as nutrients still their intake on regular basis is considered fruitful for human health. Flavonoids are biosynthesized through phenylpropanoid pathway and contain a C6-C3-C6 carbon framework. The present review has reviewed the chemistry, structure and classification of flavonoids. Additionally, their occurrence and chemical properties have also been explored. Moreover, we discuss about the different mechanisms through which flavonoids act like direct radical scavenging, leukocyte immobilization and interaction with different enzymes. Flavonoids own a number of pharmacological activities such as anti-parkinson, anti-ulcer, spasmolytic, anti-depressant, anti-bacterial, anti-hypertensive, anti-diabetic, anti-inflammatory and anti-cancer. This review intent to give healthy information for formation of new flavonoid based pharmaceutical formulation to act against various diseases.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Rana, A. C., & Gulliya, B. (2019). Chemistry and Pharmacology of Flavonoids- A Review. Indian Journal of Pharmaceutical Education and Research, 53(1), 8-20. https://doi.org/10.5530/ijper.53.1.3

    Copyright and licence

    © 2019 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. CC BY 4.0