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Review

Recent Developments on Pharmacological Potential of 1,3,4-Oxadiazole Scaffold

1, 1, 1, 1, 2

  1. 1Department of Pharmaceutical Chemistry, Delhi Institute of Pharmaceutical Sciences and Research, New Delhi, INDIA.
  2. 2School of Medical and Allied Sciences, GD Goenka University, Gurgaon, Haryana, INDIA.

CORRESPONDENCE

Bhutani Rubina

Department of Pharmaceutical Chemistry, Delhi Institute of Pharmaceutical Sciences and Research, New Delhi, INDIA.

rubinabhutani23@gmail.com

Received: 04-04-2018; Accepted: 29-12-2018.

Volume 53, Issue 2s (Supplement) · pp. s1-s16 · 2019 · DOI: 10.5530/ijper.53.2s.44

ABSTRACT

Heterocyclic compounds represent the important structural key in pharmaceutical medicinal chemistry. In literature, five-membered heterocycles are reported to be a core moiety of various pharmaceutical drugs. 1,3,4-oxadiazole scaffold, among various five-membered heterocycles is an important molecule which attracts various medicinal chemist to develop a novel biologically active molecule. 1,3,4-Oxadiazole is found to bear important pharmacological activities such as anti-diabetic, antimicrobial, anti-cancer, anticonvulsant, antioxidant, anti-Alzheimer’s, anti-inflammatory, antiviral, cardiovascular, anti-tuberculosis, anti-pyretic, insecticidal. This review compiles the biological updates on various compounds containing 1,3,4-oxadiazole as a core moiety from the recent years.

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    Rubina, B., P, P. D., Garima, K., Ravi, K., & Manni, D. (2019). Recent Developments on Pharmacological Potential of 1,3,4-Oxadiazole Scaffold. Indian Journal of Pharmaceutical Education and Research, 53(2s), s1-s16. https://doi.org/10.5530/ijper.53.2s.44

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    © 2019 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. CC BY 4.0