In vitro and in vivo Antidiabetic Activity of Ag Nanoparticles Mediated from Gymnemic Acid I and II
1, 1
- 1Department of Pharmacognosy, JSS College of Pharmacy, Ooty, Nilgiris, Tamil Nadu, INDIA.
CORRESPONDENCE
Dr. Kalakotla Shanker
Department of Pharmacognosy, JSS College of Pharmacy, Nilgiris, Tamil Nadu, INDIA.
Received: 27-08-2022; Accepted: 08-06-2023.
Volume 57, Issue 3s (Supplement) · pp. s710-s717 · 2023 · DOI: 10.5530/ijper.57.3s.80
ABSTRACT
Background: Gymnema sylvestre is traditionally used to treat diabetes in Asia.Materials and methods: GA-I and GA-II were docked to PTP 1B. Nanoparticles were produced using centrifugation green synthesis.Results: Blood glucose levels significantly decreased (p less than 0.001) at a dose of 200 mg/kg of GA-I mediated AgNPs.Conclusion: GA-I mediated AgNPs can be exploited as prospective nanomedicine for type-2 diabetes.
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Sivaramakumar, N., & Shanker, K. (2023). In vitro and in vivo Antidiabetic Activity of Ag Nanoparticles Mediated from Gymnemic Acid I and II. Indian Journal of Pharmaceutical Education and Research, 57(3s), s710-s717. https://doi.org/10.5530/ijper.57.3s.80
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