Isolation and Functioning Investigation of Salvia hispanica Seed Mucilage as a Potential Sustained Release Carrier for Water Soluble Drug
1, 2
- 1Department of Pharmaceutics, Pharmacy College, Jouf University, Sakaka, Al-jouf, SAUDI ARABIA.
- 2Departments of Pharmaceutics, Royal College of Pharmacy and Health Sciences, Berhampur, Odisha, INDIA.
CORRESPONDENCE
Dr. Dibya Sundar Panda
Department of Pharmaceutics, Pharmacy College, Jouf University, Sakaka, Al-jouf, SAUDI ARABIA.
Received: 14-09-2022; Accepted: 08-06-2023.
Volume 57, Issue 3s (Supplement) · pp. s724-s733 · 2023 · DOI: 10.5530/ijper.57.3s.82
ABSTRACT
Background: Natural biopolymers or hydrogels are explored to sustain release of water-soluble drugs.Materials and Methods: Mucilage was isolated from Salvia hispanica seeds. Gelispheres loaded with Losartan Potassium (LP) were prepared using sodium alginate, pectin and CSM.Results: Isolated mucilage possesses immense properties like consistency and excellent hydration. Developed gelispheres exhibited good mucoadhesion and sustained drug release.Conclusion: Findings advocate the use of mucilage for twice daily losartan potassium sustain release system.
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Panda, D. S., & Khandai, M. (2023). Isolation and Functioning Investigation of Salvia hispanica Seed Mucilage as a Potential Sustained Release Carrier for Water Soluble Drug. Indian Journal of Pharmaceutical Education and Research, 57(3s), s724-s733. https://doi.org/10.5530/ijper.57.3s.82
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© 2023 Author(s)
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. CC BY 4.0