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Research Progress of Baicalin Interactions with the Animal Gut Microbiome

1, 1, 1, 1, 1, 1,2

  1. 1Laboratory of Veterinary Pharmacology and Toxicology, College of Animal Science and Veterinary Medicine, Xinyang Agriculture and Forestry University, Xinyang, PEOPLE’S REPUBLIC OF CHINA.
  2. 2Laboratory of Veterinary Pharmacology and Toxicology, College of Animal Medicine, Huazhong Agricultural University, Wuhan, PEOPLE’S REPUBLIC OF CHINA.

CORRESPONDENCE

Jinzhe Li

Laboratory of Veterinary Pharmacology and Toxicology, College of Animal Science and Veterinary Medicine, Xinyang Agriculture and Forestry University, Xinyang, PEOPLE’S REPUBLIC OF CHINA.

2009200055@xyafu.edu.cn359832965@qq.com

Received: 11-02-2023; Accepted: 20-08-2023.

Volume 58, Issue 1 · pp. 64-68 · 2024 · DOI: 10.5530/ijper.58.1.6

ABSTRACT

Homeostasis of the animal gut microbiome is essential for maintaining intestinal health and normal growth and development. Baicalin is an O-glucuronidated flavonoid that possesses strong anti-bacterial, anti-inflammatory and antioxidant activities. Its addition to animal feed can alter gut microbial community composition, diversity and production of bacterial metabolites while decreasing production of pro-inflammatory cytokines and other factors that compromise the integrity of the epithelial cell barrier. This review thus summarizes the research progress of baicalin and regulation of the gut microbiota to provide guidance for the potential application of this compound for animal production as an antibiotic alternative.

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    Chen, P., Ma, B., Liu, J., Zhang, M., Li, J., & Wu, H. (2024). Research Progress of Baicalin Interactions with the Animal Gut Microbiome. Indian Journal of Pharmaceutical Education and Research, 58(1), 64-68. https://doi.org/10.5530/ijper.58.1.6

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    © 2024 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. CC BY 4.0