Table of Contents

Original Article(continued)

1. Development and Validation of a Novel UPLC-MS/ MS Method for Quantification of Tovorafenib and Characterization of its Forced Degradation Products

   Gayathridevi Ketineni, Risy Namratha Jamullamudi

   pp. 1745-1753 · DOI: 10.5530/ijper.20262058 · 2026

   Aim and Objectives: The current study was primarily aimed at the development of a validated stability indicating UPLC method for tovorafenib and its related impurities, and UPLC-MS/MS analysis of degradation products. Ma…

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2. QbD-Based Development, Greenness and Blueness Evaluation of a Stability-Indicating HPTLC Method for Ivacaftor with Mass Spectrometric Identification of Degradation Products

   Vidhya Kishore Bhusari, Nirmal Vijay Bhangale, Minal Rushikesh Ghante, Arpana Rajaram Patil

   pp. 1754-1766 · DOI: 10.5530/ijper.20262023 · 2026

   Aim/Background: Quality by Design (QbD) is a structured approach to pharmaceutical development that emphasizes a deep understanding of processes and control of variability to ensure consistent quality. This study aims to…

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3. Pharmacovigilance Education in Pharmacy: An Evaluation of Knowledge, Attitude and Perception Among Future Pharmacists

   Arfa Anwar Sayed, Akshata Gore, Shamita Shyam Sail, Sanatkumar Bharamu Nyamagoud

   pp. 1767-1776 · DOI: 10.5530/ijper.20262029 · 2026

   Background: Pharmacovigilance (Pv) comprises the detection, valuation, understanding, as well as inhibition of adverse drug events or drug related glitches. Following the thalidomide tragedies of the 1950s and 1960s, pha…

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4. Flax-Based Green-Synthesized Gold Nanoparticles Alleviate the Severity of Multiple Sclerosis Symptoms in Mice

   Yuanhong Li, Yan Jiang

   pp. 1777-1786 · DOI: 10.5530/ijper.20262115 · 2026

   Aim: This study aimed to explore the green synthesis and characterization of Gold Nanoparticles (GNPs) using an aqueous extract of Linum usitatissimum L. (Flax) and assess their potential role in neuroinflammatory diseas…

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5. Isolation and Mechanistic Exploration of FS-1: A Pro-Apoptotic Protein from Gloydius brevicaudus Venom in Tumor Cells

   Jianguo Hu, Hongxia Guo, Chuang Wang, Yun Chen

   pp. 1787-1800 · DOI: 10.5530/ijper.20262119 · 2026

   Background/Objectives: Components potentially inducing tumor cell apoptosis were isolated from Gloydius brevicaudus venom, and their apoptotic mechanisms were investigated. Materials and Methods: The lyophilized venom wa…

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6. Tumor Suppressive Effect of miRNA-205-3p on Hepatocellular Carcinoma via Regulating ZDBF2

   Xin Lu, Wenting Mi, Jianming Zheng, Meishi Tang, Haoxiang Ou, Yubin Liu

   pp. 1801-1809 · DOI: 10.5530/ijper.20264811 · 2026

   Objectives: The present study aimed to clarify the functional involvement of microRNA-205-3p (miRNA-205-3p) in Hepatocellular Carcinoma (HCC) progression and to determine its potential clinical relevance in predicting di…

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7. Relationship between miR-148a-3p and Lower Extremity Arteriosclerosis Obliterans

   Junfang Yi, Wenjiang Pan, Xiaoqiang Li

   pp. 1810-1816 · DOI: 10.5530/ijper.20264789 · 2026

   Background: Post-interventional restenosis remains a major limitation in the management of Lower Extremity Arteriosclerosis Obliterans (LEASO), and reliable circulating biomarkers for early risk prediction are still lack…

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