Volume 51, Issue 4s (Supplement)

Original Article(continued)

1. Synthesis and Biological Activity of Novel 2,5-Dichloro-3-Acetylthiophene Chalcone Derivatives

   Bontha Venkata Subrahmanya Lokesh, Yejella Rajendra Prasad, Afzal Basha Shaik

   pp. s679-s690 · DOI: 10.5530/ijper.51.4s.99 · 2017

   Objective: A series of novel 2, 5-dichloro-3-acetylthiophene chalcone derivatives were synthesized by Claisen-Schmidt condensation and evaluated for them in vitro antifungal, antitubercular activities and cytotoxic activ…

   TextPDFLens

2. Role of Ginkgo biloba Extract, Against Isoproterenol Induced Cardiac Toxicity in Rats

   Narendra Singh Badore, Prabhat Kumar Das, Sujit Pillai, Akshita Thakur

   pp. s691-s699 · DOI: 10.5530/ijper.51.4s.100 · 2017

   Objective: Ginkgo biloba is a potent antioxidant dietary source for human health. Oxidative stress through generation of free radicals damages the myocardium in different experimental condition. The present research was …

   TextPDFLens

3. Green Expedient Synthesis of Pyrimidine Derivatives via Chalcones and Evaluation of their Anthelmintic Activity

   Biswa Mohan Sahoo, Mullangi Rajeswari, Panda Jnyanaranjan, Sahoo Binayani

   pp. s700-s706 · DOI: 10.5530/ijper.51.4s.101 · 2017

   Objective: In the present study, we focused on the environment-friendly processes used for the preparation of pyrimidine derivatives with pharmacological properties. In this regard, microwave heating is used as the alter…

   TextPDFLens

4. Synthesis and in-vitro Antioxidant Activity of Novel Schiff Bases and Azetidines Derived from Phenyl Urea Derivatives

   Veera Raghavulu Nagavolu, Shankarananth Velusamy, Sridhar Chechugari, Prasanna Raju Yalavarthi, Manasa Karani

   pp. s707-s711 · DOI: 10.5530/ijper.51.4s.102 · 2017

   Objective: The Schiff bases and azetidines are important intermediates used in synthesis of several therapeutics and medicinally contributing molecules. This research was focused on synthesis of Schiff bases and azetidin…

   TextPDFLens

5. Antiobesity Potential of Fresh Cow Urine and its Distillate - A Biomedicine for Tomorrow

   Sanjay Sharma, Ketan Hatware, Ashwini Deshpande, Payal Dande, Sravani Karri

   pp. s712-s721 · DOI: 10.5530/ijper.51.4s.103 · 2017

   Background: The cow urine has been used traditionally for the management of many diseases and also used as bio-enhancer to improve their therapeutic effect. Objective: To prepare and evaluate the anti-obesity potential o…

   TextPDFLens

6. Comparative Study of Various Non-Nucleoside Reverse Transcriptase Inhibitors on Different Reverse Transcriptase Enzyme

   Shital Manoj Patil, Kalyani Dhirendra Asgaonkar, Trupti Sameer Chitre, Aditi Kinikar, Chaitali Kharat, Vaibhavi Bhoirekar, Madhura Athavale, Mitali Katkar

   pp. s722-s728 · DOI: 10.5530/ijper.51.4s.104 · 2017

   Context: Acquired immunodeficiency Syndrome (AIDS) is caused by Human immunodeficiency virus type 1 (HIV-1). 4-Thiazolidone nulecus is the target pharmacophore which have diverse biological activities including anti HIV …

   TextPDFLens

7. A Rapid and Sensitive Bio Analytical RP-HPLC Method for Detection of Docetaxel: Development and Validation

   Prachi Balaram Kharkar, Swapnil Sunil Talkar, Vandana Bharat Patravale

   pp. s729-s734 · DOI: 10.5530/ijper.51.4s.105 · 2017

   Objective: A rapid and selective high-performance liquid chromatographic (HPLC) method has been developed and validated for Docetaxel anhydrous (DTX) using Ketoconanzole (KCZ) as an internal standard in biological fluids…

   TextPDFLens

8. Phytochemical Screening and Evaluation of Cytotoxic Effect and Antioxidant Activity of Fractions Isolated from Stenochlaena palustri (Burm.f.) Bedd. Leaves

   Sangeetha Arullappan, Sakunie Sawai, Lew Ann Chee, Meerashri Mahandan, Ragaventhan Shanmugavelan

   pp. s735-s740 · DOI: 10.5530/ijper.51.4s.106 · 2017

   Introduction: Stenochlaena palustris (Burm.f.) Bedd. is an edible fern from Blechnaceae family, native to India through Southeast Asia to Polynesia and Australia. The study was conducted to evaluate the cytotoxic effect …

   TextPDFLens

9. Protective Effects of Biochanin A against Methotrexate-Induced Acute Liver Injury in Rats

   Erdem Kamil Ozer, Mustafa Tugrul Goktas, Aysun Toker, Ceyhan Ugurluoglu, Hulagu Bariskaner

   pp. s741-s746 · DOI: 10.5530/ijper.51.4s.107 · 2017

   Background: Methotrexate (MTX) is one of the most commonly used chemotherapeutic agents in the treatment of cancer patients, however its therapeutic use is limited due to dose dependent hepatotoxicity caused by oxidative…

   TextPDFLens

10. Investigation of in vitro Antioxidant and Anti-inflammatory Activities of Selected Siddha Polyherbal Formulations

    Perumal Rajalakshmi, Vellingiri Vadivel, Pemaiah Brindha

    pp. s747-s753 · DOI: 10.5530/ijper.51.4s.108 · 2017

    Objective: This study deals with the antioxidant and anti-inflammatory activities of selected Siddha polyherbal formulations such as Amukkara choornam, Thirikadugu choornam, Eladi choornam and Thiripala choornam. Amukkar…

    TextPDFLens

11. Development and Validation of UV-Spectrophotometric Method for Estimation of Metformin in Bulk and Tablet Dosage Form

    Yuvraj Dilip Dange, Sandip Mohan Honmane, Somnath Devidas Bhinge, Vijay Rajaram Salunkhe, Dhanraj Raghunath Jadge

    pp. s754-s760 · DOI: 10.5530/ijper.51.4s.109 · 2017

    Introduction: Diabetes mellitus, a metabolic disorder characterized by increased blood sugar level. Metformin hydrochloride is used to treat type I Diabetes mellitus. Metformin hydrochloride chemically 1, 1-dimethylbigua…

    TextPDFLens

12. The Development and Validation of Stability Indicating Analytical Method for Determination of Nortriptyline in Nortriptyline HCl Tablets by Liquid Chromatography

    Tukaram B Sawant, Dhananjay V. Mane

    pp. s761-s768 · DOI: 10.5530/ijper.51.4s.110 · 2017

    Purpose: To develop and validate a rapid, rugged, precise and an accurate stability indicating analytical method for determination of Nortriptyline HCl in Nortriptyline tablets. The separation of impurities and Nortripty…

    TextPDFLens

13. Stability Indicating HPLC Method Using Core Shell Stationary Phase for the Determination of Related Substances in Levocetirizine Dihydrochloride Oral Solution

    Venkata Krishna Akula, Barij Nayan Sinha, Han Jeong seok

    pp. s769-s775 · DOI: 10.5530/ijper.51.4s.111 · 2017

    Rationale: Levocetirizine (LCZ) is a new generation antihistamine drug used for the allergic symptoms resulting from various diseases. The present research work focuses on the development of a simple and precise HPLC met…

    TextPDFLens

14. Development and Validation of UV-Derivative Spectroscopic and RP-HPLC Methods for the Determination of Amlodipine Besylate and Valsartan in Tablet Dosage form and Comparison of the Developed Methods by Student’s T-Test

    Usharani N, Divya K, Ashrtiha VVS

    pp. s776-s782 · DOI: 10.5530/ijper.51.4s.112 · 2017

    Introduction: Hypertension is directly responsible for 51% of all stroke deaths and 45% of all coronary heart diseases worldwide. Amlodipine besylate is a calcium channel blocker used as an anti-hypertensive agent. Valsa…

    TextPDFLens

15. Development and Validation of Inductively Coupled Plasma Atomic Emission Spectroscopy [ICP-AES] Analytical Method for Estimation of Cisplatin in Biological Samples

    Shruti Akshay Wagle, Darshana Jain, Sudha Rathod, Rajani Athawale, Amrita Bajaj

    pp. s783-s789 · DOI: 10.5530/ijper.51.4s.113 · 2017

    Objective: Cisplatin, a popular anti-neoplastic agent is employed as a first line treatment for variety of cancers. Majority of the analytical methods reported for Cisplatin are either complex or not suitable for routine…

    TextPDFLens