Volume 59, Issue 1s (Supplement)

Joy Das, Utpal Bhui, Shreya Chowdhary, Subhajit Sarkar, Indra Kumar Ghoshal, Soumyadip Nayak, Rahul Bishayee, Navneet Khurana, Bimlesh Kumar, Neha Sharma

pp. s1-s15 · DOI: 10.5530/ijper.20250179 · 2025

Neurodegenerative diseases constitute a pressing global health challenge, characterized by the gradual loss of neuronal function and structure, leading to cognitive impairment and motor deficits. Biomarkers play a crucia…

Dilend Patle, Narendra Pratap Singh Sengar

pp. s16-s24 · DOI: 10.5530/ijper.20255296 · 2025

Background: This comprehensive review highlights the importance of bio-conjugated metallic complexes in drug design, particularly in the field of metallo-pharmaceutical science. The review emphasizes the need for biologi…

Sadhana Sharma, Chandana Majee, Rupa Mazumder, Avijit Mazumder, Pankaj Kumar Taygi, Sachin Kumar Singh

pp. a25-a45 · DOI: 10.5530/ijper.20250270 · 2025

Oxadiazoles and their derivatives represent a significant class of organic compounds, wielding profound implications in both the realms of medicinal science and heterocyclic rings housing oxygen and nitrogen atoms, has g…

Kanika Vats, Kuldeep Singh

pp. s46-s51 · DOI: 10.5530/ijper.20255637 · 2025

This study examined the present situation of Antimicrobial Resistance (AMR) and prevailing Antimicrobial Stewardship Programs (ASP), and its impact during COVID-19 globally and specifically in Abu Dhabi, UAE aiming to id…

Pankaj Sharma, Pradhyumn Shivhare, Vinay Jain

pp. s52-s62 · DOI: 10.5530/ijper.20250092 · 2025

Background: Nonsteroidal anti-inflammatory drugs, or NSAIDs, including mefenamic acid, are commonly used for the relief of moderate to serious pain. However, their poor water solubility affects their bioavailability and …

Shyam Ghadlinge, Preeti Sable, Swaroop Lahoti, Jaiprakash Sangshetti

pp. s63-s70 · DOI: 10.5530/ijper.20254202 · 2025

Background: Azilsartan, a poorly soluble angiotensin receptor blocker belonging to BCS class II, faces challenges related to low solubility and bioavailability. To address these issues, this study compares two formulatio…

Sankaranarayanan Vijayalakshmi, Somaskandan Subramanian, Sellappan Malathi

pp. s71-s80 · DOI: 10.5530/ijper.20254852 · 2025

Background: The complex physicochemical properties of the lipids have considerable impact on the solubility and stability of the Lipid Based Nanocarriers (LBN). The major challenge in the successful development of LBN li…

Bhuvnesh Kumar Singh, Nishi Sharma, Sumit Durgapal, Mahandra Rana, Ashok Kumar Rajpoot, Kajal Gurow, Vaishali

pp. s81-s88 · DOI: 10.5530/ijper.20255365 · 2025

Background: Conventional eye formulations are generally flushed away from the lacrimal area due to the rapid elimination of drugs from this region, with only a small amount being absorbed. The short-term precorneal conta…

Ramya Teja Medarametla, Gadela Venkata Radha

pp. s89-s101 · DOI: 10.5530/ijper.20255427 · 2025

Aim/Background: The aim of this study was to enhance the bioavailability of Enzalutamide by developing cross-linked cyclodextrin nanosponges loaded with the drug (EZL-CDNS). The objective of the work is to thoroughly inv…

Aiswarya Gangadheran Nambiyar, Brindha Durairaj

pp. s102-s113 · DOI: 10.5530/ijper.20255549 · 2025

Background: Phloridzin, a plant compound is of interest in the field of research due to its antioxidant, anti-inflammatory, anticancer and antidiabetic activity. The current study's objectives were to create, characteriz…

Archana Dhyani, Ganesh Kumar

pp. s114-s120 · DOI: 10.5530/ijper.20255777 · 2025

Background: Ocular drug delivery is hindered by a number of reasons, including nasolacrimal drainage, tear turnover and eye blinking. One of the important factors is rapid removal of drug from the eye. The fast eliminati…

Anuya Vimalakar Babar, Kishori Prasanna Sutar, Siddarth Vijay Usulkar

pp. s121-s131 · DOI: 10.5530/ijper.20254263 · 2025

Objectives: The aim of the present study is to formulate and evaluate acyclovir loaded aspasomal topical gel by using Aloe vera gel base to enhance skin permeation and reduce the associated oral side effects of acyclovir…

Yashavanth Gangadhar, Amal Rasul Al Turaifi, Nimbagal Raghavendra Naveen, Prakash Goudanavar, Santhosh Fattepur, Nagaraja Sreeharsha, Mohammed Monirul Islam, Muhammad Shahzad Chohan

pp. s132-s137 · DOI: 10.5530/ijper.20251137 · 2025

Aim: To evaluate the pharmacokinetics and toxicity properties of Valganciclovir Hydrochloride, a potent antiviral agent, using in silico models. Background: Valganciclovir Hydrochloride is an FDA-approved antiviral agent…

Girish Meravanige, Mallamma Thippeswamy, Predeepkumar Narayanappa Shiroorkar, Nimbagal Raghavendra Naveen, Prakash Goudanavar, Nagaraja Sreeharsha

pp. s138-s150 · DOI: 10.5530/ijper.20250001 · 2025

Introduction: Tuberculosis (TB) remains one of the leading causes of infectious deaths worldwide, ranking second only to COVID-19. The rise of Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR) TB strains hig…

Jineetkumar Gawad, Chandrakant Bonde, Smita Bonde, Mayank Sharma, Dinesh Suthar, Mahesh Palkar, Vishal Beldar, Bharat Dhokchawle, Vaishali Raghuwanshi

pp. s151-s158 · DOI: 10.5530/ijper.20256810 · 2025

Aim/Background: Tuberculosis (TB) is a severe airborne infectious disease caused by Mycobacterium tuberculosis, a contagious bacillus and the second leading cause of mortality. A pivotal obstacle in Tuberculosis (TB) the…

Anish John, Sreehari Malangai Subramanyabhat, Masmarika Mohan, Anoop Narayanan Vadakkepushpakath, Gunimala Chakraborty, Manohar Mahadev

pp. s159-s168 · DOI: 10.5530/ijper.20256334 · 2025

Background: The objective of this research was to develop a nano emulsion of ipriflavone (IP nano emulsion), a soy isoflavone to enhance its solubility, bioavailability and bone regeneration potential. Materials and Meth…

Saif Aboud M Alqahtani

pp. s169-s178 · DOI: 10.5530/ijper.20255187 · 2025

Background: Thyroid disorder is one of the most prevalent critical issues for public health in clinical practice. Lipid profiles and cardiovascular attenuation are significantly affected by thyroid dysfunction. Thyroid d…

Zeenath Banu, Shaista Samreen, Safura Ayesha Mujeeb

pp. s179-s189 · DOI: 10.5530/ijper.20250031 · 2025

Background: Manilkara zapota, a plant with a rich history in traditional medicine, holds potential as a therapeutic agent. However, its neuroprotective properties remain largely unexplored, highlighting the need for furt…

Soumik Bhattacharjee, Abhik Si, Amit Kumar Halder, Sumit Nandi

pp. s190-s197 · DOI: 10.5530/ijper.20250199 · 2025

Background: The prime objective of the investigation is to measure the capability of expanding the enumeration of platelet in rodent model utilizing hydro-alcoholic extract of Psidium guajava L. fruit in addition with in…

Gatla Venkata Amruthavalli, Arumugam Vijayalakshmi

pp. s198-s213 · DOI: 10.5530/ijper.20255476 · 2025

Aim: Broccoli fiber has enormous safety net as well as high pre-biotic value. Amoxicillin is although an effective drug against infections is equally harmful to gut microbiota and therefore the above side-effect impedes …