Indian Journal of Pharmaceutical Education and Research · Archive
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In this issue
1–20 of 28Original Article
Santosh Kumar Panda, Manoranjan Sahu, Kahnu Charan Panigrahi, Chinam Niranjan Patra
pp. s213-s224 · DOI: 10.5530/ijper.53.3s.90 · 2019
Objective: The objective of this study was to systematically develop with Quality by Design (QbD) approach of Effervescent Floating Multiple unit Minitablets (EFMM) of metoprolol succinate (MS) for once-a-day dosing usin…
Prasanna Laxmi, Abhishek Varma, Aravind Pai, Muddukrishna Badamane Sathyanarayana
pp. s225-s230 · DOI: 10.5530/ijper.53.3s.91 · 2019
Objectives: This current research work aimed for improvement of the solubility and permeability of poorly permeable Doxorubicin HCl through generating co-crystals. The main goal for the preparation of oral drugs is to de…
Disha Kesharwani, Sandhya Mishra, Swarnali Das Paul, Rishi Paliwal, Trilochan Satapathy
pp. s231-s238 · DOI: 10.5530/ijper.53.3s.92 · 2019
Objective: The poor solubility which causes the poor bioavailability of simvastatin is an arduous task for the preparation of oral dosage form, which can be increased by the preparation of solid dispersion. Materials and…
Shan Mohanan, Sajan Jose
pp. s239-s245 · DOI: 10.5530/ijper.53.3s.93 · 2019
Introduction: The aim of the study is to develop a galactomannan-based drug delivery system. In this work galactomannan, a biocompatible polymer was isolated from a novel plant source. The seeds of the indigenous plant C…
Daphisha Marbaniang, Ratna Jyoti Das, Paulami Pal, Ananta Saikia, Manash Pratim Pathak, Santa Mandal, Nilutpal Sharma Bora, Anup Kumar Das, Pronobesh Chattopadhyay, Subhabrata Ray, Bhaskar Mazumder
pp. s246-s254 · DOI: 10.5530/ijper.53.3s.94 · 2019
Aims: Microballoons are floating particulate system comprising of a hollow core, drug being loaded within the polymeric layer. The aim of the study was to prepare microballoons containing extract of Clerodendrum colebrok…
Gunasekaran Shylaja, Arunachalam Sathiavelu
pp. s255-s263 · DOI: 10.5530/ijper.53.3s.95 · 2019
Background: Endophytic fungi are one of the most promising resources of natural bioactive products. In the present study, secondary metabolites were isolated from the endophytic fungus Chaetomium cupreum and evaluated in…
Bilal Çakir, İbrahim Gülseren
pp. s264-s272 · DOI: 10.5530/ijper.53.3s.96 · 2019
Background: Cherry laurel fruits are characterized by their dark color and rich phenolic contents. Previously, phenolic extracts from cherry laurel varieties were shown to demonstrate anti-proliferative activities agains…
Sugandha Chaudhari, Shitalkumar Zambad, Mohammed Ali
pp. s273-s279 · DOI: 10.5530/ijper.53.3s.97 · 2019
Background: Concomitant administration of herbs and synthetic drugs causes pharmacokinetic and pharmacodynamic interactions. Objectives: To investigate pharmacokinetic and pharmacodynamic interactions between Syzygium cu…
Kamal Kant, Uma Ranjan Lal, Manik Ghosh
pp. s280-s287 · DOI: 10.5530/ijper.53.3s.98 · 2019
Background: Pathogenic bacteria (Gram positive/Gram negative) are serving as a vital precursor for the development of infectious diseases in humans. Arisaema tortuosum (Wall.) Schott (ATWS), a famous folklore medicine of…
Neha Verma, Usha Chouhan
pp. s288-s298 · DOI: 10.5530/ijper.53.3s.99 · 2019
Aim: The increasing incidences of type 2 diabetes mellitus, represents a considerable public health problem and characterized by loss in sensitivity of tissues to insulin which can be restored by activation of Peroxisome…
Aravinda Pai, Jayashree B.S
pp. s299-s312 · DOI: 10.5530/ijper.53.3s.100 · 2019
Aim/Background: Quantitative structure activity relationship studies are important ligandbased methods used in drug discovery process. The development of Quantum mechanics and its application in the study of smaller and …
Aravinda Pai, B.S. Jayashree
pp. s313-s324 · DOI: 10.5530/ijper.53.3s.101 · 2019
Aim/Background: Chalcones are one of the important class of compounds possessing a wide range of biological properties [Dinmock 1999, Go 2005]. One of the extensive area in research on chalcones is expressed in terms of …
Judy Jays, Shamanna Mohan, Janardhanan Saravanan
pp. s325-s331 · DOI: 10.5530/ijper.53.3s.102 · 2019
Escherichia coli is the predominant gram negative bacteria responsible for a variety of hospital-acquired infections and urinary tract infections. As the bacterial strains are rapidly acquiring resistance to the availabl…
Vishal Shivalingappa Patil, Prakash Rajashekhar Biradar, Vasim Attar, Pukar Khanal
pp. s332-s337 · DOI: 10.5530/ijper.53.3s.103 · 2019
Introduction: Thiazolidinedione’s are widely used synthetic antidiabetic agents. These agents affect the pumping power of heart muscle due to the formation of edema; limiting their usage in patients with congestive heart…
Sadhana Jangbahadur Rajput, Mansi Anuj Sathe
pp. s338-s346 · DOI: 10.5530/ijper.53.3s.104 · 2019
Background: Cyproheptadine HCl is a serotonin antagonist and histamine H1 blocker agent. Objective: The objective of the present work was to establish a rapid, sensitive and validated bioanalytical HPLC method using Liqu…
Ashiyana Mansuri, Sonal Desai
pp. s347-s355 · DOI: 10.5530/ijper.53.3s.105 · 2019
Background: A new, simple, accurate and precise High Performance Liquid Chromatographic method (HPLC-UV) has been developed and validated in accordance with ICH guidelines for the determination of gallic acid in Lohasava…
Aarti Abhishek Shah, Yogendra Nayak
pp. s356-s363 · DOI: 10.5530/ijper.53.3s.106 · 2019
Background: Trans-resveratrol is a naturally occurring polyphenolic compound extensively marketed as a nutraceutical. It is highly explored molecule in the research community with vast therapeutic potential. Therefore, m…
Muralikrishna Ramisetti, Lakshmana Rao Atmakuri, Basaveswara Rao Mandava Venkata, Vinayender Adireddy
pp. s364-s372 · DOI: 10.5530/ijper.53.3s.107 · 2019
Objective: The main objective of this work was to develop a simple, rapid and sensitive liquid chromatography/tandem mass spectrometry (LC–MS/MS) method for the simultaneous quantification of Canagliflozin and Metformin.…
Palled Mahesh Shivabasappa, Hadaki Diksha, Mahendra Kumar Chouhan, Sunil Satyappa Jalalpure, Shailendra Suryawanshi Sanjay
pp. s373-s379 · DOI: 10.5530/ijper.53.3s.108 · 2019
Background: The combination of Ciprofloxacin and Ornidazole is used for the effective treatment of intra-abdominal infections. Many branded and generic combined dosage formulations of Ciprofloxacin and Ornidazole are ava…
Rajesh Kumar Chawla, Subhranshu Panda, Kulandaivelu Umasankar, Siva Prasad Panda, Dalu Damayanthi
pp. s380-s386 · DOI: 10.5530/ijper.53.3s.109 · 2019
Objective: A simple, accurate and economical method has been developed by Reverse Phase High Performance Liquid Chromatography (RP-HPLC) using indirect UV (Ultra Violet) method. The Principle behind the indirect UV metho…