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In this issue

1–20 of 24

Review Article

  1. Bhutani Rubina, Pathak Dharam P, Kapoor Garima, Kant Ravi, Dutta Manni

    pp. s1-s16 · DOI: 10.5530/ijper.53.2s.44 · 2019

    Heterocyclic compounds represent the important structural key in pharmaceutical medicinal chemistry. In literature, five-membered heterocycles are reported to be a core moiety of various pharmaceutical drugs. 1,3,4-oxadi…

  2. Chandrakantsing Vijaysing Pardeshi, Abhijeet Dattatraya Kulkarni, Raju Onkar Sonawane, Veena Shailendra Belgamwar, Prashant Jagannath Chaudhari, Sanjay Javerilal Surana

    pp. s17-s27 · DOI: 10.5530/ijper.53.2s.45 · 2019

    The modulation of mucoadhesion at the nanoscale is a very challenging task before the formulation scientists. Mucoadhesive nanoparticles are endowed with distinct properties such as increased residence, intimate contact …

  3. Abhishek Shah, Richard Lobo, Nandakumar Krishnadas, Raviteja Surubhotla

    pp. s28-s42 · DOI: 10.5530/ijper.53.2s.46 · 2019

    Antioxidant potential of sesamol has led to being studied extensively in recent decades for its beneficial role in vast aliments. There has been a renewed interest in this compound recently, due to its activities such as…

Original Article

  1. Sree Harsha Nagaraja, Bandar E Al-Dhubiab, Rakesh Kumar Tekade, Katharigatta Narayanaswamy Venugopala, Ravindra Vasant Ghorpade, Girish Meravanige, Ahmed Alqadheeb

    pp. s43-s49 · DOI: 10.5530/ijper.53.2s.47 · 2019

    Background: Vildagliptin is an extensively studied DPP-4 inhibitors (anti-diabetic drug) which has contributed greatly to the understnading of molecular interatcion with the DPP-4 enzyme. However, Vildagliptin exerts glu…

  2. Ankita Vernekar, Rajashree Gude, Nidhi Ghadi, Steffi Parab, Akshata Shirodker

    pp. s50-s57 · DOI: 10.5530/ijper.53.2s.48 · 2019

    Objective: The main objective of this study was to formulate transdermal gels containing Flurbiprofen microsponges for controlled drug delivery. Methods: Microsponges containing Flurbiprofen and ethylcellulose were prepa…

  3. Uzair Nagra, Sherjeel Adnan, Sana Shafqat, Maryam Shabbir, Sajid Ali, Anum Zafar, Syed Saeed ul Hassan, Javed Iqbal

    pp. s58-s65 · DOI: 10.5530/ijper.53.2s.49 · 2019

    Aim: The sustained release tablets of Aceclofenac were prepared and evaluated for the sustained release drug profile with an aim to reduce dosing frequency and provide patient compliance. Materials and Method: The tablet…

  4. Vidya Sabale, Omprakash Nanalaji Kumawat, Prafulla Madhukarrao Sabale

    pp. s66-s73 · DOI: 10.5530/ijper.53.2s.50 · 2019

    Objective: To develop bioadhesive ocular inserts of Olopatadine hydrochloride for treating the allergic eye conditions with sustained ocular delivery which will reduce dosing frequency. Methods: Matrix type ocular insert…

  5. Om Shelke, Amol Kulkarni

    pp. s74-s81 · DOI: 10.5530/ijper.53.2s.51 · 2019

    Aim/Background: Nifedipine (NIF) is act as Calcium channel blocker which belongs to chemical class dihydropyridine and used in the treatment of hypertension. An anal fissure (AF) is the most common anorectal conditions e…

  6. Harshita Krishnatreyya, Sanjay Dey, Paulami Pal, Pranab Jyoti Das, Vipin Kumar Sharma, Bhaskar Mazumder

    pp. s82-s92 · DOI: 10.5530/ijper.53.2s.52 · 2019

    Aim: The objective of this study was to develop suitable lipid nanocarriers for topical delivery of Piroxicam, known for its anti-inflammatory and anti-arthritic properties and to increase its therapeutic potential and r…

  7. Ranjit Prasad Swain, Avasarala Nagamani, Panchagnula Udaya Shankar

    pp. s93-s103 · DOI: 10.5530/ijper.53.2s.53 · 2019

    Introduction: Combination therapy of ezetimibe and atenolol is highly desirable for better management of dyslipidaemia and hypertension. Ezetimibe has poor solubility hence variable and low bioavailability. Atenolol has …

  8. Karthik Gourishetti, Sawan Ghetia, Ligin Jacob, Sanchari Basu Mallik, Pawan Ganesh Nayak, Anoop Kishore, Krishnadas Nandakumar, Sulaiman Mohammed Alnaseer, Shalam Mohamed Hussain

    pp. s104-s111 · DOI: 10.5530/ijper.53.2s.54 · 2019

    Background: Medhya Rasayana (MR) is an ayurvedic formulation used to rejuvenate the intellectual functions. It was shown to improve the cognitive function in rats. Hence, the present study was designed to study the neuro…

  9. Neethu Kamarudheen, Thahiya Naushad, Kokati Venkata Bhaskara Rao

    pp. s112-s120 · DOI: 10.5530/ijper.53.2s.55 · 2019

    Context: Although there is an abundance of several microbial phyla in the oceans actinobacteria have emerged as a major source for natural products. Streptomyces sps is the widely encountered actinobacteria. Lately, Stre…

  10. Rohith Ganapathi Bhatta, Sadashivaiah Rudragangaiah, Satheesha Babu Birur Kotappa

    pp. s121-s128 · DOI: 10.5530/ijper.53.2s.56 · 2019

    Aim: The present research work involves the development and optimization of an in-situ gel forming formulation by face centered central composite response surface design methodology to increase buoyancy and controlled re…

  11. Gopal Krishna Padhy, Jagadeesh Panda, Ajaya Kumar Behera

    pp. s129-s134 · DOI: 10.5530/ijper.53.2s.57 · 2019

    Background: Emergence of resistance to accessible anticancer drugs became a threat to human lives in the recent time. To address this issue, discovery of novel anticancer agents becomes very essential. Benzimidazoles and…

  12. Sri Agus Sudjarwo, Giftania Wardani, Koerniasari Eraiko, Koerniasari Koerniasari, Ernawati Ernawati

    pp. s135-s142 · DOI: 10.5530/ijper.53.2s.58 · 2019

    Background: The antioxidants can be used for protective in oxidative stress that is one of the important mechanisms of lead acetate-induced lung toxicity. Objective: The current study was carried out to evaluate the effe…

  13. Mohammad Yasir, Pushpendra Singh, Sunidhi Chohan, Rahul Shrivastava

    pp. s143-s150 · DOI: 10.5530/ijper.53.2s.59 · 2019

    Aim/Background: Tuberculosis is a serious health issue across the world. Various bioactive molecules show the affects against Multidrug-resistant tuberculosis (MDR-TB). There are various standard drugs developed against …

  14. Chunhui Rao, Zhuping Hong, Yuanyuan Yao, Gang Zheng, Saisai Wang

    pp. s151-s158 · DOI: 10.5530/ijper.53.2s.60 · 2019

    Background: 18β-glycyrrhetinic acid (18β-GA) is reported to possess various pharmacological properties of which anti-inflammatory activities has been widely explored. However, the role of 18β-GA in Staphylococcus aureus …

  15. Anshul Kumar, Manish Kumar Mishra, Afeefa Afeefa, Chandrashekar K.S, Girish Pai, Vasudev Pai

    pp. s159-s163 · DOI: 10.5530/ijper.53.2s.61 · 2019

    Background: Lozenges are solid dosage form which are intended to slowly dissolve in the mouth for therapeutic effect. Common cold and flu are common diseases which usually infects the respiratory tract including symptoms…

  16. Hari Om Saxena, Ganesh Pawar

    pp. s164-s169 · DOI: 10.5530/ijper.53.2s.62 · 2019

    Introduction: Solanum indicum L. is one of the species of Dashmularishta, a wellestablished ayurvedic medicine used in the treatment of fatigue, oral sores and gynecological disorders. The present investigation dealt wit…

  17. Harshita Mishra, Pawan Kumar Mishra, Manu Jaggi, Zeenat Iqbal, Sushama Talegaonkar

    pp. s170-s178 · DOI: 10.5530/ijper.53.2s.63 · 2019

    Background: Dual loaded liposomes have always been a hot topic of investigation because of their therapeutic advantages over single drug regimens. But simultaneous estimation of both the drugs during in vitro and in vivo…