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In this issue

1–20 of 25

Original Article

  1. Keerthana Chandrasekar, Nakka Gautam Sai, Princy Sabu John, Sruthi Ninan, Raja Durai, Sivasankaran Ponnusankar

    pp. 1-7 · DOI: 10.5530/ijper.54.1.1 · 2020

    Post-Stroke Depression (PSD) is a psychiatric disorder associated with stroke which has an adverse effect on the cognitive function and survival. It usually develops in 40% of the stroke survivors within 3 months. We per…

  2. Pooja Umesh Pherwani, Sadhana Sathaye

    pp. 8-16 · DOI: 10.5530/ijper.54.1.2 · 2020

    Osteoporosis is a condition of compromised bone quality and bone density increasing the chances of fracture. In osteoporotic bone, there is a mismatch between bone formation and resorption. The high probability in both w…

  3. Hua Li, Xiaohua Shi

    pp. 17-21 · DOI: 10.5530/ijper.54.1.3 · 2020

    Aim: This study aims to evaluate the efficiency of the achievement degree for engineering education certification, example as pharmaceutical separation engineering course. The calculating method of achievement degree abo…

  4. Ahmed Abdelrahman Albarraq, Hafiz Antar Makeen, David Banji

    pp. 22-30 · DOI: 10.5530/ijper.54.1.4 · 2020

    Objectives: Pharmacy program offers many entrepreneurial opportunities in hospital, community and industrial sectors. Entrepreneurship is recognized, implemented and encouraged in many Universities around the world as a …

  5. Vinayak Shivamurthi Mastiholimath, Coutinho Tracy Whitney Valerie, Vinodkumar Shrishailappa Mannur, Panchaxari Mallappa Dandagi, Anand Panchaxari Gadad, Pukar Khanal

    pp. 31-45 · DOI: 10.5530/ijper.54.1.5 · 2020

    Aim: The main aim of this research work was to formulate, characterize and evaluate solid lipid nanoparticles containing Silver sulfadiazine. Materials and Methods: Solid lipid nanoparticles were prepared by hot homogeni…

  6. Nagaraja SreeHarsha, Jagadeesh Gurupadayya Hiremath, Suhas Sarudkar, Mahesh Attimarad, Bandar Al-Dhubiab, Anroop Balachandran Nair, Katharigatta Narayanaswamy Venugopala, Afzal Haq Asif

    pp. 46-54 · DOI: 10.5530/ijper.54.1.6 · 2020

    Background: The success of a drug primarily depends on its bioavailability. By enhancing the solubility and dissolution properties of drugs that are scarcely water soluble, significantly improves their bioavailability. M…

  7. Vinayak Shivamurthi Mastiholimath, Bhagat Ankita Rajendra, Vinodkumar Shirshalappa Mannur, Panchaxari Mallappa Dandagi, Anand Panchaxari Gadad, Pukar Khanal

    pp. 55-67 · DOI: 10.5530/ijper.54.1.7 · 2020

    Aim: The objective of the present study was to develop and evaluate cefixime nanosuspension to enhance its oral bioavailability. Materials and Methods: The method used was solvent/ antisolvent method in which methanol an…

  8. Souvik Nandi, Satyaki Aparajit Mishra, Rudra Narayan Sahoo, Rakesh Swain, Subrata Mallick

    pp. 68-72 · DOI: 10.5530/ijper.54.1.8 · 2020

    Background: Tablet manufacturing with direct compression is one of the leading industrial technique that consumes less time, labour and economic also. But the choice of excipients are critical in this case which will all…

  9. Praveen Sivadasu, Devagowda Vishakante Gowda, Nithin Kundachira Subramani, Bhavya Malgur Vishweshwaraiah, Sachhidananda Shivanna, Siddaramaiah Hatna

    pp. 73-84 · DOI: 10.5530/ijper.54.1.9 · 2020

    Background: Systemic drug delivery in schizophrenia is a major challenge, owing to the Blood-brain Barrier (BBB) and P-glycoprotein related effects. Consequently, herein an attempt is made to systemically deliver the mos…

  10. Dhana Sekaran Ganesan, Mohamed Asik Raj Mohamed, Pema Lhanzin, Kathirvel Neelan, Lakshmanan Vadakkuvaselvi, Sellamuthu Subramani, Arulvasu Chinnasamy

    pp. 85-94 · DOI: 10.5530/ijper.54.1.10 · 2020

    Background: For the past two decades, few conotoxins entered in clinical trial and some are available for pain relieving as well as for treatment of neurological disorders. Aim: The present investigation was made to eluc…

  11. Sanjiv Karale, Yamuna PV, Jagadish V Kamath

    pp. 95-100 · DOI: 10.5530/ijper.54.1.11 · 2020

    Aim: The aim of the present study was to evaluate the Cardioprotective effect of Capsaicin (CAP) against Doxorubicin (DOX) induced cardiotoxicity in experimental rats. Methods: The 24 wistar rats were randomly divided in…

  12. Iman Hassan Abdoon, Bushra Parveen, Bashier Osman, Mona S Mohamed, Wadah JA Osman, Sayeed Ahmad

    pp. 101-107 · DOI: 10.5530/ijper.54.1.12 · 2020

    Background: Plant-based remedies play a crucial role as powerful health aid worldwide. In recent years, the usage of complementary and alternative medicines has grown rapidly. The objective of the present study was to ev…

  13. Shubhangi Pawar, Shubham Khairnar, Vinod Patil, Rajendra Bhambar

    pp. 108-113 · DOI: 10.5530/ijper.54.1.13 · 2020

    Background: Neuropathic Pain (NP) is less or symptomatically managed by presently available therapeutics. Therefore developing more effective drugs with minimum adverse effects is essential. Vanillic acid is phenolic sec…

  14. Anika Jain, Nivya James, Veerapapillai Shanthi, Karuppasamy Ramanathan

    pp. 114-124 · DOI: 10.5530/ijper.54.1.14 · 2020

    Background: The increasing cases of non-small cell lung cancer pose a relentless threat to human health. Therefore, using fragment-based drug discovery as the modus operandi, the present study aimed to design small molec…

  15. Ahsas Goyal, Debapriya Garabadu

    pp. 125-134 · DOI: 10.5530/ijper.54.1.15 · 2020

    Aim/Background: The level of phosphorylated Estrogen Receptor alpha (ERα) in the nucleus was investigated in different memory-sensitive brain regions of estrogendeficient female rats. Further, the levels of cyclic nucleo…

  16. Soumendra Darbar, Srimoyee Saha, Kausikisankar Pramanik, Atiskumar Chattopadhyay

    pp. 135-142 · DOI: 10.5530/ijper.54.1.16 · 2020

    Objectives: Toxicity is an expression of being poisonous, indicating the state of adverse effects led by the interaction between toxicants and cells. The present study was designed to evaluate the acute oral toxicity stu…

  17. Dureshahwar Khan, Mubashir Mohammed, Aman Upaganlawar, Chandrashekhar D. Upasani, Hemant D. Une

    pp. 143-149 · DOI: 10.5530/ijper.54.1.17 · 2020

    Background: Neuropathy can be induced in rats by peripheral injuries, depending on compression of complete or a section of sciatic nerve and chemically by Streptozotocin (STZ). Materials and Methods: In the present study…

  18. Shila Jain, Puran Lal Sahu, Srashti Raj, Abhinav Shrivastava, Ashok Kumar Maurya, Rajiv Kumar Tonk, Kapendra Sahu

    pp. 150-154 · DOI: 10.5530/ijper.54.1.18 · 2020

    Background: A simple, sensitive and accurate method for the determination of procaterol in human urine was developed and validated using Gas Chromatography coupled to tandem mass spectrometry (GC-MS/MS) as per the requir…

  19. Kalpana Govindbhai Patel, Seena Ghanshyam Kumar Patel, Purvi Apurva Shah, Devang Bhagvandas Tandel, Tejal Ricky Gandhi

    pp. 155-165 · DOI: 10.5530/ijper.54.1.19 · 2020

    Objectives: The present research study focuses on the development of the highperformance thin layer chromatographic method using design of experiment approach for the simultaneous estimation of Azelastine hydrochloride a…

  20. Muhammad Shahzad Chohan, Rafea Elamin Elgack Elgorashe, Abdulmalek Ahmed Balgoname, Mahesh Attimarad, Nagaraja SreeHarsha, Katharigatta Narayanaswamy Venugopala, Anroop Balachandran Nair, Shinu Pottathil

    pp. 166-174 · DOI: 10.5530/ijper.54.1.20 · 2020

    Background: Diclofenac Sodium (DCL) and Moxifloxacin HCl (MOX) were simultaneously used after cataract surgery to reduce the post-operative inflammation and to control infection respectively. Objectives: Three simple, ac…