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In this issue

1–20 of 35

Review Article

  1. Saurabh Dahiya, Rokshi Rokshi, Yachika Goyal, Chanchal Sharma

    pp. s1-s8 · DOI: 10.5530/ijper.58.1s.1 · 2024

    Cosmetics still have a glitzy attraction, but the public is increasingly concerned about their toxicity. Since 2500 BC, one way of enhancing the beauty of lips has been using lipstick compositions. Lip care cosmetic prod…

  2. Kunjbihari Sulakhiya, Sushim Kanchan, Haroon Ansari, Anglina Kisku

    pp. s9-s25 · DOI: 10.5530/ijper.58.1s.2 · 2024

    Drug safety is an important factor considered during the drug discovery and development stages to develop safe and efficacious medicines for patients. Post-marketing surveillance is the commonly used method to obtain Adv…

  3. Avneet Kaur, Ashok K. Shakya, Rohit Singh, Reena Badhwar, Shalini Kapoor Sawhney

    pp. s26-s39 · DOI: 10.5530/ijper.58.1s.3 · 2024

    Cancer is the second leading cause of the death worldwide. As per the reports published by WHO, the cases of cancer in the world will increase to 22 million by 2030. Many resources are investigated all around the world f…

  4. Ruchi Sharma, Chandana Majee, Rupa Mazumder, Swarupanjali Padhi, Fahad Khan, Rashmi Saxena Pal

    pp. s40-s57 · DOI: 10.5530/ijper.58.1s.4 · 2024

    Around 10% of the world’s population suffers from liver disease, making it one of the deadliest diseases in the world. Flavonoids are a class of phenolic substituents present in a wide range of vegetables and fruit and h…

  5. Nitin Bire, Vinayak Walhekar, Omkar Makane, Pranali Yelchatwar, Amol Muthal, Subhash Bodhankar, Chandrakant Bagul, Dileep Kumar, Baswaraju Macha, Raghavendra Kulkarni, Vaibhav Shinde, Ravindra Kulkarni

    pp. s58-s66 · DOI: 10.5530/ijper.58.1s.5 · 2024

    Tuberculosis is a pathogenic infection that has created trepidation around the globe due to its repercussion on the health of patients. The iron transport mechanism in mycobacterium plays a pivotal role in bacterial surv…

Original Article

  1. Ajay Singh Bisht, Divya Juyal

    pp. s67-s72 · DOI: 10.5530/ijper.58.1s.6 · 2024

    Background: In present study 1,3,4-oxadiazole was attempted to synthesize from nicotinic acid and further their amino acid derivates were formed. Amino acids play a significant role in biological system. Only 20 amino ac…

  2. Prafulla Sabale, Lata Potey, Suchita Waghmare, Nusrat Sayyad, Vidya Sabale

    pp. s73-s79 · DOI: 10.5530/ijper.58.1s.7 · 2024

    Objectives: To synthesize a novel series of 3-(Aryl/Heteroaryl)-5-Methyl-7-Phenyl [1,2,4]triazolo[4,3a]Pyrimidines (5a-i). Materials and Methods: Synthesis was carried out though the microwave assisted synthesis, Spectro…

  3. Sonakshi Tyagi, Salahuddin Salahuddin, Avijit Mazumder, Rajnish Kumar, Vimal Datt, Km. Shabana, Abhishek Shankar Sharma, Mohamed Jawed Ahsan, Mohammad Shahar Yar

    pp. s80-s92 · DOI: 10.5530/ijper.58.1s.8 · 2024

    Aim/Background: Novel quinoline compounds containing benzimidazole have been synthesized in a number of different ways and screened for anti-epileptic potential through in vivo and in silico studies. Materials and Method…

  4. Kavitha K, Mohan S, Jothikanth. V, Srinivasan N, Manojkumar S, Esakiprasanth. R, Bakitha Jessila M, Revathi P, Venkatesh V, Subash M

    pp. s93-s102 · DOI: 10.5530/ijper.58.1s.9 · 2024

    Aim: The configuration found programmed recreation ligand-receptor relations were worn during rework also rationale of investigate in order to establish budding bio-energetic candidate seeing that (Enoyl-ACP)-Enoyl-acyl …

  5. Sanjeevani Shekhar Deshkar

    pp. s103-s112 · DOI: 10.5530/ijper.58.1s.10 · 2024

    Aim/Background: Venlafaxine HCl (VEN) is an antidepressant drug with extensive first pass metabolism and low oral bioavailability. In the present study, a solid self-emulsifying formulation of Venlafaxine was developed a…

  6. Challa Taraka Ramarao, Suvvari Bhagya Laxmi

    pp. s113-s125 · DOI: 10.5530/ijper.58.1s.11 · 2024

    Background: Mirtazapine widely prescribed Antidepressant drug that belongs to BCS Class II drug with low solubility and high permeability characteristics. Aim: The Box Behnken design was used to statistically optimize th…

  7. Prativa Das, Jnyanaranjan Panda, Goutam Kumar Jena, Chinam Niranjan Patra, Kahnu Charan Panigrahi

    pp. s126-s138 · DOI: 10.5530/ijper.58.1s.12 · 2024

    Purpose: To improve the oral bioavailability as well as the physical stability of nimodipine, Design-Expert-driven nimodipine loaded nanoemulsifying drug delivery system was developed with a certain quality target produc…

  8. Suddala Shirisha, Sunit Kumar Sahoo, Tallam Veena, Yamsani Madhusudan Rao

    pp. s139-s148 · DOI: 10.5530/ijper.58.1s.13 · 2024

    Background: Promethazine Hydrochloride is a water-soluble drug and it suffers from poor bioavailability (25%) when given through oral route due to extensive first-pass metabolism. To overcome hepatic first pass metabolis…

  9. Archana Dhyani, Ganesh Kumar

    pp. s149-s157 · DOI: 10.5530/ijper.58.1s.14 · 2024

    Aim: The purpose of the study was development and evaluation of Atenolol loaded microsponge in situ gel for the management of ocular hypertension, glaucoma. Materials and Methods: The microsponges were prepared by modifi…

  10. Patel Rajendra, Parmar Komal

    pp. s158-s166 · DOI: 10.5530/ijper.58.1s.15 · 2024

    Background: Abiraterone acetate is an anticancer molecule indicated for prostate cancer. The purpose of this study was to develop a nanosuspension of abiraterone acetate in order to improve its solubility, dissolution pr…

  11. Kiran Kumar Yadiki, Umashree Kokatanur, Panchaxari Mallappa Dandagi, Sujay Hulyalkar

    pp. s167-s175 · DOI: 10.5530/ijper.58.1s.16 · 2024

    Background: The in situ gel, which after gelation floats in the stomach, is appropriate for sustaining drug release. Aqueous extract of liquorice used for the treatment of peptic ulcers and Helicobacter pylori, was used …

  12. Nagasen Dasari, Chirravuri Satyanarayana Phani Kumar, Rama Krishna Gummadi, Sai kiran Pindiprolu, Sujiya Balla, Amala Masa, Lavanya pulidindi, Vajrapu Subhaveera Prasanth

    pp. s176-s186 · DOI: 10.5530/ijper.58.1s.17 · 2024

    Objectives: The objective of this study was to develop a stable and effective form of an Orodispersible tablet containing Nicardipine Hydrochloride for the immediate treatment of high blood pressure and angina. The aim w…

  13. Santosh S. Chhajed, Umesh D. Laddha, Sandeep S. Sonawane, Mrunal Pekhale, Prajakta Thorat, Sanjay J. Kshirsagar, Jaipraksh N. Sangshetti

    pp. s187-s195 · DOI: 10.5530/ijper.58.1s.18 · 2024

    Background: Fungal infections are the primary cause of skin diseases. Topical application of antifungal drugs is the most preferred treatment which is associated with key limitations viz. need for high doses and frequenc…

  14. Sridevi Gowripattapu, SathisKumar Dinakaran, Selvamuthukumar Subramanian

    pp. s196-s205 · DOI: 10.5530/ijper.58.1s.19 · 2024

    Introduction: Rosuvastatin is a statin drug used to lower cholesterol, but it has poor water solubility and low bioavailability, limiting how effective it can be. The objective of the present study was to formulate and e…

  15. Chandrashekar Ranga, Tanveer Naved, Arti Thakkar

    pp. s206-s211 · DOI: 10.5530/ijper.58.1s.20 · 2024

    Background: The vaccine is a means to control and eradicate infectious diseases and also to strengthen health systems. There should be a complete ecosystem in a well-defined, transparent, and predictable regulatory syste…