Indian Journal of Pharmaceutical Education and Research · Archive
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In this issue
21–40 of 47Original Article(continued)
Changqing Li, Junpeng Meng
pp. 1555-1563 · DOI: 10.5530/ijper.20261510 · 2026
Background: Ischemic Stroke (IS) is a serious illness with great fatality and disability globally. The pathophysiological causes of IS are oxidative stress, apoptosis and neuroinflammation. Objectives: Cerebral Ischemia/…
Hui Wang, Jie Xia
pp. 1564-1571 · DOI: 10.5530/ijper.20261715 · 2026
Objectives: To elucidate the underlying mechanism through which Dihydroartemisinin (DHA) exerts its influence on mice with Neuropathic Pain (NP) induced by the NS1 protein of the Japanese Encephalitis Virus (JEV). Materi…
Xiaoyu Ren, Jinfeng Wang, Yuan Zhou, Lili Jiang, Fei Liu, Qingxian Mei
pp. 1572-1578 · DOI: 10.5530/ijper.20261835 · 2026
Aim/Background: To study the improvement effect of Phellinus linteus polysaccharides (Phps) on doxorubicin-induced myocarditis injury in mice. Materials and Methods: The mice were randomly divided into 5 groups, namely b…
Annu Bhati, Avijit Mazumder, Priyanka Bansal, Motamarri Venkata Naga Lalitha Chaitanya
pp. 1579-1586 · DOI: 10.5530/ijper.20262755 · 2026
Background: Liver disorders arising from various causes, including infections, toxins, and certain medications, remain a significant global health challenge. Ongoing research focuses on the development of novel drug comp…
Yang Xu, Jianmin Zhang, Yapu Zhang, Yanli Gou, Qian Wang, Xuezhong Li, Kai Li
pp. 1587-1595 · DOI: 10.5530/ijper.20263001 · 2026
Background: Renal fibrosis, a defining feature of Chronic Kidney Disease (CKD) development, is marked by the over deposition of extracellular matrix proteins, resulting in structural and functional impairment of the kidn…
Qun Li, Yuancheng Jin, Yuhua Wu, Menglu Zhu, Saiwei Wu, Guoqing Zhang, Zhujin Song
pp. 1596-1605 · DOI: 10.5530/ijper.20260395 · 2026
Background: Depression is a commonly occurring mental disease and many active ingredients of herbs have been proven to effectively alleviate depression. Objectives: To investigate the effects of Tanshinone IIA (Tan IIA) …
Abdulkarim S. Binshaya, Khalid Alshaghdali
pp. 1606-1617 · DOI: 10.5530/ijper.20261291 · 2026
Background: Cyclophosphamide (Cy) is widely used in oncology and immunology for treating cancers and severe autoimmune diseases. However, its clinical utility is limited by adverse effects such as immunosuppression, hema…
Yang Liu, Boer Deng, Dan Luo, Jianjun Zhang, Weimin Kong
pp. 1618-1623 · DOI: 10.5530/ijper.20260473 · 2026
Background: To investigate the effects of metformin on the proliferation and apoptosis of human endometrial carcinoma cells, along with elucidating the potential underlying mechanisms, we conducted a study wherein the ca…
Abdulmajeed M. Jali, Ali Hanbashi, Hamad Al Shahi, Faroq Kamli, Khalid Zoghebi
pp. 1624-1635 · DOI: 10.5530/ijper.20264716 · 2026
Background and Objectives: Lung cancer is a prevalent malignancy characterized by a high propensity for metastasis and is a rising contributor to mortality. The prognosis and treatment strategies have become challenging …
Xiao-lin Li, Sheng-fu Chen, Tian-long Liu, Ren-jie Wang, Rong Wang, Mao-Xing Li
pp. 1636-1645 · DOI: 10.5530/ijper.20260479 · 2026
Aim: Geniposide is the main active ingredient in Gardenia jasminoides Ellis, but its antipyretic mechanism is still unclear. Materials and Methods: To study the change of the gut microbiota in febrile rats with dry yeast…
Qian Li, Yuechuan Zhang, Tianjiao Wang, Jiamei Wu
pp. 1646-1655 · DOI: 10.5530/ijper.20261024 · 2026
Background: Previous research has demonstrated that glycyrrhizin exhibits antioxidant, anti-inflammatory and antiapoptotic characteristics. In this study, RD cells were infected with Enterovirus 71 (EV71) and a cell mode…
Padmapriya Sundaram, Selvi Sellappan, Mohammed Saleh Al Aboody, Wardah A. Alhoqail, Suresh Mickymaray, Kaviya Suresh
pp. 1656-1669 · DOI: 10.5530/ijper.20264744 · 2026
Background: Medicinal plants remain an important source of therapeutic agents due to their rich phytochemical composition and broad pharmacological activities. Simarouba glauca is a traditionally used medicinal plant; ho…
Qiangdong Zou, Yan Wang
pp. 1670-1680 · DOI: 10.5530/ijper.20261329 · 2026
Background: Premature ovarian failure (POF), clinically referred to as primary ovarian insufficiency (POI), represents a loss of ovarian function occurring before the age of 40 and remains a major cause of infertility in…
Hafiz A. Makeen, Mohammad Albratty
pp. 1681-1695 · DOI: 10.5530/ijper.20264949 · 2026
Background: Osteosarcoma is a predominant bone cancer characterised by increased metastatic potential, rapid proliferation, and insufficient clinical prognosis, making it the leading cause of cancer-related morbidity. Fi…
Hongxing Xue, Weijuan Nan, Qiang Li
pp. 1696-1705 · DOI: 10.5530/ijper.20262570 · 2026
Aim/Background: Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder with limited therapeutic options. Tephrosin (TP), a natural rotenoid, exhibits antioxidant and anti-inflammatory properties. This study…
Hongli Yang, Qian Sun, Zhi Hao, Nana Li, Wei Liu, Fanjia Zeng, Dandan Liu, Zhibin Jiang
pp. 1706-1712 · DOI: 10.5530/ijper.20263131 · 2026
Background: Thyroid cancer, a tumor arising from the thyroid gland, impacts a considerable portion of the population, with incidence rates exhibiting an upward trend globally. The mortality rates for thyroid cancer are r…
Samar Zuhair Alshawwa, Lama AlRebdi, Nouf AlMasri, Mayada AlSuwaid, Amal Alnajjar, Reem Bahmaid, Faisal AlQarni, Khaled AlMatrafi, Sadaf Jamal Glani
pp. 1713-1719 · DOI: 10.5530/ijper.20261849 · 2026
Background: Patients with Familial Hypercholesterolemia (FH) or statin intolerance are significantly increasing. Therefore, a novel class of lipid-lowering drugs called Proprotein Convertase Subtilisin Kexin type 9 (PCSK…
Kavitha Kandasamy, Zain Alabden Ghanim Ahmed Ahmed, Zead Helmi Abudayeh, Samer Hasan Hussein-Al-Ali, Shilpa Perumal Narasimhamoorthi, Palanisamy Arulselvan, Karunakaran Saravanan, Subbarayan Sarathbabu
pp. 1720-1729 · DOI: 10.5530/ijper.20264263 · 2026
Introduction: The primary trigger of End-Stage Renal Disease (ESRD) in several affluent nations, including the US, is diabetic nephropathy. Objectives: Diabetic nephropathy is a microvascular consequence that can occur i…
Mehmet Özsan, İlknur Ündağ, Nurcan Dönmez, Elif Aydın, Hasan Hüseyin Dönmez
pp. 1730-1735 · DOI: 10.5530/ijper.20263488 · 2026
Background and Aim: Bisphenol A (BPA) est chemicum endocrinum perturbans, late in variis productis consumptoriis adhibitum, quod per systemata endocrinum et immunologicum nocet valetudini. Huius studii propositum erat ex…
Hemlata Manohar Nimje, Smita Pawar, Amol Kale, Trushal Chorage
pp. 1736-1744 · DOI: 10.5530/ijper.20260817 · 2026
Objectives: The focus of this research work was to develop an accurate and validated RP-HPLC technique for analysing Favipiravir (FAVI) drug and interpreting related degradants in drug and its formulation. Materials and …