Indian Journal of Pharmaceutical Education and Research · Archive
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In this issue
21–40 of 40Original Article(continued)
Xuefei Li, Cong Fu, Shanshan Tang, Jian Yang, Xiaonan Shi, Shanshan Cui
pp. 1059-1066 · DOI: 10.5530/ijper.20251152 · 2025
Objectives: In the study, we analyzed the effect of Atractylodes macrocephala Koidz Polysaccharide (AMKP) on Breast Cancer-Related Depression (BCRD) to provide new references for future treatment of BCRD. Materials and M…
Abuzer Ali, Amena Ali
pp. 1067-1077 · DOI: 10.5530/ijper.20256422 · 2025
Objectives: Earlier findings revealed the importance of different natural compounds and synthetic drugs in the treatment of cancer by targeting Phosphoinositide 3-Kinase (PI3K). In the direction to discover novel PI3K in…
Yan Wang, Changle Chen
pp. 1078-1084 · DOI: 10.5530/ijper.20251049 · 2025
Aim: Lung Carcinoma (LC) is still one of the malignant neoplastic diseases with the fastest-growing morbidity and mortality worldwide. This study observes the influence of traditional Chinese medicine acupuncture and mox…
Chepattu Mohammed Abdullah Anzar, Molath Varkey Joseph, Ramachandran Sundaram, Bharadwaj Gururaj Vadiraj, Padmanabhan Chettayil Prasad, Bineesh Earanimose, Neethumol Benny
pp. 1085-1092 · DOI: 10.5530/ijper.20251039 · 2025
Background: The aging process of RPE (Retinal Pigment Epithelium cells) and the effects of blue light are caused by a high level of oxidative stress, which makes these cells susceptible to malfunctioning, cellular senesc…
Liqin Sun, Bin Song, Zhining Yu, Jiajia Jiang
pp. 1093-1099 · DOI: 10.5530/ijper.20250959 · 2025
Background: Breast cancer caused 670,000 deaths worldwide in 2024. Saponarin (SAP) is mostly present in vegetables and citrus fruits and has demonstrated encouraging anti-proliferative properties in various studies. This…
Jiaying Fan, Lin Zhao
pp. 1100-1108 · DOI: 10.5530/ijper.20251173 · 2025
Background: Pneumonia is a prevalent acute respiratory illness that impacts the alveoli and the distal airways and if left untreated, it presents a significant health challenge. It is linked to elevated rates of illness …
Mohammed Mousa AlZharani, Eman Abdullah Almuqri, Mohammed Mubarak Ahmed, Shaikha A Albatli, Nada Hamad Aljarba, Hassan Ahmed Rudayni, Khadijah Nasser Yaseen, Saad Hussin Alkahtani, Fahd Ali Nasr, Amin Abdullah AlDoaiss, Mohammed Saad AlEissa
pp. 1109-1117 · DOI: 10.5530/ijper.20250489 · 2025
Background: Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are among the most prescribed pharmaceuticals worldwide. Similar to other NSAIDs, mefenamic acid possesses anti- inflammatory, analgesic and antipyretic properti…
Yang Xu, Xijie Zheng, Zhenzhen Hao
pp. 1118-1127 · DOI: 10.5530/ijper.20251645 · 2025
Background: Diabetes mellitus is a chronic metabolic disorder defined by hyperglycemia, potentially resulting in various consequences, such as diabetic kidney disease. Diabetic kidney disease is a major health concern as…
Deepak Kumar Jha, Saroj Kumar Sah, Mehdi Fathima
pp. 1128-1136 · DOI: 10.5530/ijper.20250943 · 2025
Objectives: The main objective of this study is to develop a method for in vitro T cell proliferation from rat peripheral blood mononuclear cells. Materials and Methods: The study involved female adult Albino Wistar rats…
Jitao Yang, Xuyang Xie, Jialu Liu, Yuheng Fan, Qiang Deng
pp. 1137-1143 · DOI: 10.5530/ijper.20254530 · 2025
Aim: This study aims to examine the effects of puerarin on blood fluoride, micro-Computed Tomography (micro-CT) parameters and bone histomorphology of rats with fluorosis and to investigate whether puerarin has therapeut…
Fayou Zhou, Jizhi Zhou, Huadong Mao, Huadong Mao, Liwei Yang, Xiangtao Wang
pp. 1144-1150 · DOI: 10.5530/ijper.20251188 · 2025
Aim/Background: Calycosin is a primary glycoside derived from the Chinese medicinal plant Radix astragali (RA). The compound has been demonstrated to suppress cell growth and trigger programmed apoptosis in various cance…
Synthesis and in vitro Evaluation of Zinc Ferrite Nanospheres for Sustained Carvedilol Drug Delivery
Vijayalakshmi Sundaram, Balaji Dhandapani
pp. 1151-1159 · DOI: 10.5530/ijper.20251251 · 2025
Background: Magnetic nanoparticles has significant applications, in MRI contrast enhancement, tissue regeneration, cancer therapy, controlled drug delivery etc. The nanoparticles can be tailored to possess specific attri…
Abdullah Farasani, Siddig Ibrahim Abdelwahab
pp. 1160-1169 · DOI: 10.5530/ijper.20251812 · 2025
Background: Diabetes mellitus is a persistent metabolic condition that has emerged as a major public health issue globally. The prevalence of diabetes has been rapidly increasing, posing a major challenge to global healt…
Weiwei Chen, Jingran Fu, Yaya Cheng, Abdullah A Alarfaj, Abdurahman Hajinur Hirad
pp. 1170-1179 · DOI: 10.5530/ijper.20250634 · 2025
Background: In many instances, Recurrent Spontaneous Abortion (RSA) has unexplained etiology and does not have any prognostic clues. Antioxidant vitamins are closely related to a series of diseases, including RSA. Howeve…
Amit Suryakant Tapkir, Sneha Nandkumar Rashinkar, Ashok Bhau Pathak, Sandip Murlidhar Bhagat, Alka Ramesh Bhure, Sheetal Dhiraj Chaudhari, Anuradha Ghanshyam More
pp. 1180-1186 · DOI: 10.5530/ijper.20250721 · 2025
Aim/Background: Throughout the drug development process, maintaining control over impurities and keeping them within specified limits is of paramount importance in the production of high-quality drugs. Numerous studies h…
Rina Ikhar, Prafulla Sabale, Komal Somkuwar, Vaibhav Sawale, Vidya Sabale, Amol Warokar
pp. 1187-1193 · DOI: 10.5530/ijper.20250546 · 2025
Introduction: In the present study, quantification of tofacitinib citrate by UV spectroscopy and HPTLC method were done and validated as per ICH guidelines. Tofacitinib was approved in 2012, it was first JAK inhibitor fo…
Saidatu Hajar Izam Mohd Mukhtar, Chia Wei Phan, Syireen Alwi, Noorasyikin Shamsuddin
pp. 1194-1203 · DOI: 10.5530/ijper.20255209 · 2025
Background: Aphrodisiac is a substance used to treat sexual dysfunction and boost performance in sexual activity. Aphrodisiac Herbal Products (AHP) was associated with numerous safety issues. The internet has become a pi…
Sudipta Ghosh, Chiranjib Bhowmik, Ashish Goel, Deeya Bandyopadhyay, Nripen Mondal, Sudipta Sinha, Gayatri Singh, Amitava Ray
pp. 1204-1220 · DOI: 10.5530/ijper.20255228 · 2025
Aim/Background: Early in the COVID-19 epidemic, the dire need for effective and readily available outpatient therapies became apparent as healthcare systems worldwide faced unprecedented strain. This study addressed the …
Norah Saeed Al-Zahrani, Ayyub Ali Patel, Basiouny El-Gamal, Mohamed Abd Ellatif, Khalid Ali Nasif, Mohamed Babiker Abd Elrouf, Heitham Mutwakil Mohammed, Safaa Omer, Marwa Saeed, Muniera Mohieldeen, Hagar Mohamed Mohamed, Mohammad Rehan Ajmal
pp. 1221-1230 · DOI: 10.5530/ijper.20251022 · 2025
Background: A common element of the tumor microenvironment, cancer-associated fibroblasts play a major role in the development of breast cancer via a variety of pathways. Studies show that cancer-associated fibroblasts o…
Menaka Kaliyan, Senthilkumar Palaniappan
pp. 1231-1237 · DOI: 10.5530/ijper.20255148 · 2025
Background: The management of diabetes is a global health challenge. Non-adherence to medication in chronic diabetics is a severe issue that is linked to negative consequences, which can be related to various factors. Th…